CLARO

A collaborative multi-source radiopathomics project for personalized oncology in non-small cell lung cancer.

CLARO

Clinical Application

CLARO

A collaborative multi-source radiopathomics project for personalized oncology in non-small cell lung cancer.

RadioPathomics Personalized Oncology Decision Support

Overview

CLARO was born from a collaborative project between the Faculties of Medicine and Surgery and Engineering, with the aim of identifying imaging characteristics specific to lung cancer and using them as biomarkers to predict response to oncological therapies.

The project combines radiological and anatomo-pathological images with other clinical information to build personalized image-analysis models for stage III-IV non-small cell lung cancer. The goal is to convert heterogeneous medical data into a single and interpretable biomarker signature to support precision medicine.

Research Directions

  • Imaging characteristics specific to lung cancer used as biomarkers for response prediction.
  • Multimodal analysis of radiological and anatomo-pathological images with clinical information.
  • Quantitative biomarker signatures for therapy selection in stage III-IV non-small cell lung cancer.

Related Publications

  1. A deep learning approach for overall survival prediction in lung cancer with missing values
    Camillo Maria Caruso, Valerio Guarrasi, Sara Ramella, and Paolo Soda
    2024
    clinical prediction oncology
  2. Deep pathomics: A new image-based tool for predicting response to treatment in stage III non-small cell lung cancer
    Lorenzo Nibid, Carlo Greco, Ermanno Cordelli, Giovanna Sabarese, Michele Fiore, Charles Z. Liu, Edy Ippolito, Rosa Sicilia, Marianna Miele, Matteo Tortora, and 5 more authors
    2023
    radiomics oncology medical imaging